
When we launched Driven to Discover, we invited you to ask your single greatest question and received over 5,000! Here are some great ones answered by U of M experts.
In our society, its wrong to make fun of ethnic/social minorities. Why is it totally acceptable to be cruel to (even discriminate against) the obese?  |      | Is there an alternative to using embryos in stem cell research and how viable would such an alternative be?  |      | Do we have memories stored from before we were born?  |      | What if everyone in the world took the day off?  |      | How closely is ones sense of smell linked to memory?  |      | What is the human carrying capacity of the Earth?  |      | Why do songs get stuck in your head, and its almost impossible to get them out?  |      | What are the chances of intelligent life in outer space?  |      | Why do we forget things? Is there a way to remember everything we read, see, or feel other than by "memorizing them"?  |      | My dog exhibits strange behavior shortly before a thunderstorm begin. Can dogs sense a change in weather?  |      | Will we ever have a planned stabilization and reduction of world population?  |      | Should people with developmental disabilities be allowed to be parents?  |      | Why do we enjoy eating junk food and not healthy food? Why not make healthy food delicious?  |      | How is it possible for the Mississippi River, which originates from a low altitude (about 500m), flow about 4,000 miles across the country?  |      | Why do we believe in things that we have no proof of?  |      | Whats better for the environment, a real Christmas tree or an artificial one?  |      | Why is it that the heart does not get cancer as often as other organs in the body?  |      | How can no two people have the same DNA (excluding twins)?  |      | How "fluid" is the incidence of poverty in the metro area? in the nation? That is, do poor people remain poor or is it a temporary condition?  |      | Where will the penguins go when the icebergs melt?  |      |
In our society, its wrong to make fun of ethnic/social minorities. Why is it totally acceptable to be cruel to (even discriminate against) the obese?  |      | Discrimination against the obese is not acceptable, says Dr. Charles Billington, associate director of the Minnesota Obesity Center. But, he added, common misconceptions about obesity and the obese make such discrimination all too commonplace. “Many of my colleagues refer to bias against the obese, ironically, as the last safe prejudice,” Billington says. “But the fact that it happens doesn’t make it right, of course.” Billington co-authored a study on obesity bias in which researchers asked attendees at the opening session of the Obesity Society’s annual meeting to associate words such as “obesity” and “thinness” with descriptor words such as “good, bad, lazy, and hard-working.” While researchers surmised that the study’s participants, being knowledgeable about obesity, would be among the least likely to discriminate against them, the results revealed that even this group was more likely to associate negative character traits with obesity and positive ones with thinness. Such a bias stems from misconceptions, Billington says. “There is a common belief among the population at large and also to a large extent among health professionals that obese people are responsible for their own problem,” Billington says. “The implicit assumption is that they have the choice to not to be obese.” That view doesn’t mesh with the emerging body of scientific knowledge which that indicates that obesity has complex biological causes, he says. Such causes include genetic predisposition, abnormal brain mechanics controlling such functions such as appetite and activity, and “the ecology of human beings,” which causes us to shape our environment in ways that are more enjoyable or convenient for us, but ultimately contribute to obesity. “We can have more donuts. We can have more driving and less walking. We can have whatever we want,” Billington says. “But to see those choices as just free choices that we can make outside of the context of joint biology is just missing the point.” Understanding the causes of obesity may help reduce discrimination, Billington says. “There are very strong and important reasons not to discriminate against the obese,” he says. “Particularly, if you recognize it’s not their fault.” Charles J. Billington is a professor in the Department of Medicine and associate director of the Minnesota Obesity Center.

| Is there an alternative to using embryos in stem cell research and how viable would such an alternative be?  |      | Do we have memories stored from before we were born?  |      | What if everyone in the world took the day off?  |      | How closely is ones sense of smell linked to memory?  |      | What is the human carrying capacity of the Earth?  |      | Why do songs get stuck in your head, and its almost impossible to get them out?  |      | What are the chances of intelligent life in outer space?  |      | Why do we forget things? Is there a way to remember everything we read, see, or feel other than by "memorizing them"?  |      | My dog exhibits strange behavior shortly before a thunderstorm begin. Can dogs sense a change in weather?  |      | Will we ever have a planned stabilization and reduction of world population?  |      | Should people with developmental disabilities be allowed to be parents?  |      | Why do we enjoy eating junk food and not healthy food? Why not make healthy food delicious?  |      | How is it possible for the Mississippi River, which originates from a low altitude (about 500m), flow about 4,000 miles across the country?  |      | Why do we believe in things that we have no proof of?  |      | Whats better for the environment, a real Christmas tree or an artificial one?  |      | Why is it that the heart does not get cancer as often as other organs in the body?  |      | How can no two people have the same DNA (excluding twins)?  |      | How "fluid" is the incidence of poverty in the metro area? in the nation? That is, do poor people remain poor or is it a temporary condition?  |      | Where will the penguins go when the icebergs melt?  |      |
In our society, its wrong to make fun of ethnic/social minorities. Why is it totally acceptable to be cruel to (even discriminate against) the obese?  |      | Is there an alternative to using embryos in stem cell research and how viable would such an alternative be?  |      | “To answer this question, it is important to recognize that there are many different types of stem cells, and they can come from either embryos or other cells and tissues. The stem cells that come from non-embryonic sources are termed “adult” stem cells. Adult stem cells include blood stem cells, liver stem cells, muscle stem cells, skin stem cells, etc. “Typically adult stem cells make only cells of one body part: blood stem cells make all different blood cells, neural stem cells make neurons and supporting cells of the brain and spinal cord, liver stem cells make liver and biliary cells, and so on. Indeed, bone marrow transplantation done to treat patients with certain types of cancer involves the transfer of blood stem cells (that reside in the bone marrow) from one person to another. “Therefore, the short answer to this question is yes—stem cell research and some therapies that do not involve embryos are actually now done on a routine basis. However, there are many diseases where a part of the body is diseased or damaged for which adult stem cells are insufficient. “Embryonic stem cells are known to have the ability to form all the cells and tissues of the body. This vast potential makes embryonic stem cells very exciting as a source to better treat and potentially cure a wide variety of diseases, such as Parkinson’s Disease, diabetes, heart damage, and cancer, to name a few. There are some exciting studies that suggest some adult stem cells may have greater potential to make a wide variety of cell types, described as greater “plasticity,” however those studies remain very preliminary. “Therefore, embryonic stem cells provide a crucial new research resource, and potentially a source of new clinical therapies. Derivation of embryonic stem cells does involve the use embryos. However, it is important to recognize that all embryos used for this research come from fertility clinics and they would all be discarded if not used for this important area of research. It is estimated more than 400,000 embryos are currently frozen in fertility clinics. Therefore, even if human embryonic stem cell research was prohibited, the number of human embryos saved would be zero – they will all be discarded anyway. Since these embryos were developed to give life, a truly pro-life position is to use the extra embryos for life-saving research and therapies. “Even so, some are interested in derivation of embryonic stem cells without destroying or damaging the rest of the embryo. However, this has not yet been found feasible. Indeed, even trying to achieve this goal would be considered “embryo research” and would likely still require the destruction or damage to some human embryos. Embryonic stem cells, as currently derived, are considered the “gold standard” for stem cell research, and there is no replacement for these cells in the foreseeable future. “The approach at the Stem Cell Institute at the University of Minnesota is to use all available resources, adult and embryonic stem cells, to maximize our ability to find new treatments for currently incurable diseases that afflict millions of people.” Dan S. Kaufman, MD, Ph.D. Stem Cell Institute and Department of Medicine Division of Hematology, Oncology, and Transplantation


| Do we have memories stored from before we were born?  |      | What if everyone in the world took the day off?  |      | How closely is ones sense of smell linked to memory?  |      | What is the human carrying capacity of the Earth?  |      | Why do songs get stuck in your head, and its almost impossible to get them out?  |      | What are the chances of intelligent life in outer space?  |      | Why do we forget things? Is there a way to remember everything we read, see, or feel other than by "memorizing them"?  |      | My dog exhibits strange behavior shortly before a thunderstorm begin. Can dogs sense a change in weather?  |      | Will we ever have a planned stabilization and reduction of world population?  |      | Should people with developmental disabilities be allowed to be parents?  |      | Why do we enjoy eating junk food and not healthy food? Why not make healthy food delicious?  |      | How is it possible for the Mississippi River, which originates from a low altitude (about 500m), flow about 4,000 miles across the country?  |      | Why do we believe in things that we have no proof of?  |      | Whats better for the environment, a real Christmas tree or an artificial one?  |      | Why is it that the heart does not get cancer as often as other organs in the body?  |      | How can no two people have the same DNA (excluding twins)?  |      | How "fluid" is the incidence of poverty in the metro area? in the nation? That is, do poor people remain poor or is it a temporary condition?  |      | Where will the penguins go when the icebergs melt?  |      |
In our society, its wrong to make fun of ethnic/social minorities. Why is it totally acceptable to be cruel to (even discriminate against) the obese?  |      | Is there an alternative to using embryos in stem cell research and how viable would such an alternative be?  |      | Do we have memories stored from before we were born?  |      | Newborn babies definitely have memories from before they were born, says cognitive development specialist Dr. Kathleen Thomas. And while those memories might still reside somewhere in the furthest reaches of our adult brains, a condition known as “infantile amnesia” keeps us from accessing those memories. Infantile amnesia isn’t true amnesia, which is a medical ailment that can result from disease or trauma, Thomas says, but instead is a phenomenon that keeps us from being able to recollect, as adults, anything in our lives before age two or three. “There are so many developmental changes that occur during the transition from infancy to toddlerhood to preschool age, including language acquisition and identity development,” says Thomas, an associate professor of child psychology in the University’s Institute of Child Development and director of the Cognitive Developmental Neuroimaging Laboratory. “Scientists believe that these changes may alter the way memories are stored and accessed; so even though we still have our memories from the earlier period, we can no longer access them.” Researchers have definitively determined that infants have memories from before they were born. For example, laboratory experiments clearly show that babies can remember and recognize their mother’s voice over another woman’s voice almost immediately after birth. Changes in brainwaves, even while sleeping, signal the babies’ response and recognition. Other studies have shown that babies will prefer a book their mothers repeatedly read to them in utero over other books. Scientists believe the babies prefer the frequently read stories because they remember them. Infantile amnesia is both a fascinating phenomenon and a frustrating component of early memory research, Thomas says. “We know that as adults we can’t remember that far back and with infants we can’t say to them, ‘So, now tell me everything you remember.’” Scientists continue to explore new ways to get a clearer picture of what memories are locked away in our brains’ inner recesses and to determine what biological or evolutionary purposes they may serve. Dr. Kathleen (Katie) Thomas is associate professor of child psychology in the Institute of Child Development and director of the Cognitive Developmental Neuroimaging Laboratory which explores the development and neurobiological correlates of cognitive development, particularly learning and memory, during the preschool and school age periods.

| What if everyone in the world took the day off?  |      | How closely is ones sense of smell linked to memory?  |      | What is the human carrying capacity of the Earth?  |      | Why do songs get stuck in your head, and its almost impossible to get them out?  |      | What are the chances of intelligent life in outer space?  |      | Why do we forget things? Is there a way to remember everything we read, see, or feel other than by "memorizing them"?  |      | My dog exhibits strange behavior shortly before a thunderstorm begin. Can dogs sense a change in weather?  |      | Will we ever have a planned stabilization and reduction of world population?  |      | Should people with developmental disabilities be allowed to be parents?  |      | Why do we enjoy eating junk food and not healthy food? Why not make healthy food delicious?  |      | How is it possible for the Mississippi River, which originates from a low altitude (about 500m), flow about 4,000 miles across the country?  |      | Why do we believe in things that we have no proof of?  |      | Whats better for the environment, a real Christmas tree or an artificial one?  |      | Why is it that the heart does not get cancer as often as other organs in the body?  |      | How can no two people have the same DNA (excluding twins)?  |      | How "fluid" is the incidence of poverty in the metro area? in the nation? That is, do poor people remain poor or is it a temporary condition?  |      | Where will the penguins go when the icebergs melt?  |      | | |